The majority of autoantibodies found in SLE-associated thrombocytopenia are antiplatelet surface glycoproteins (i.e., anti-GPIIb/IIIa), similar to those found in the course of ITP, but the exposure of platelet to cardiolipin-like membrane phospholipids can also lead to the production of anticardiolipin antibodies. This evidence concerns the gene ITGA2B and Thrombocytopenia.