Interestingly, as stated by Stasi et al., the administration of immunosuppressive therapies to treat thrombocytopenia during APS reduces the titers of anti-GP antibodies that could be detected in APS (and in ITP without APS as well), but not the titers of aPL [18], thus suggesting that thrombocytopenia during APS could be a clinically independent entity due to antibodies different from those detected in ITP. The gene discussed is FASLG; the disease is autoimmune polyendocrinopathy.