Antiphospholipid antibody syndrome (APS) is an autoimmune acquired thrombophilia characterized by recurrent thrombosis and pregnancy morbidity in the presence of antiphospholipid antibodies (aPL), namely anticardiolipin antibodies (aCL), anti-β2 glycoprotein I (Anti-β2GPI) antibodies, and lupus anticoagulant (LA) [1,2,3]. This evidence concerns the gene APOH and autoimmune polyendocrinopathy.