Thomi et al. confirmed that it was upregulated at the peptide level in lesional HS skin and, in an interesting way, they showed that LL-37 peptide levels in lesional HS skin positively correlated with both the presence of T cells, macrophages, and neutrophils, and mRNA levels of the Th1/Th17-associated cytokines IFN-γ, IL-17, IL-23, IL-1β, TNF-α, and IL-32 [101]. The gene discussed is IL1B; the disease is histiocytic sarcoma.