CRH and Behcet disease: Moreover, Rats exposed a to binge-like alcohol drinking during adolescence showed altered CRH levels in the NAc (Kruskal–Wallis test: p < 0.001), where CRH immunostaining was significantly increased at WD1, with respect to CTRL (Dunn’s post hoc test: p = 0.0133), and at WD10 with respect to CTRL (p < 0.0001) and BD (p = 0.0054) rats (Figure 2F,G).