NEGR1 and hydrops fetalis: In female mice, on the 6th week of diet, the blood sugar levels of the HF-diet-fed Negr1−/− mice were significantly higher at 30 min (p = 0.0004) and 60 min (p = 0.0171) timepoints compared to regular-chow-fed Negr1−/− mice, and, for the HF-diet-fed WT mice, the blood sugar levels were significantly higher at 30 min (p < 0.0001) and 60 min (p = 0.0003) timepoints (Figure 3h).