Finally, several differences were also identified within the SF groups, including many proteins up-regulated in SF1 compared to SF2 and SF3 groups, related to lipid and carbon metabolism, diabetes or insulin resistance, among others: Acetoacetyl-CoA synthetase (AACS), Acetyl-CoA carboxylase (ACACA), Carnitine O-palmitoyl-transferase 1 (CPT1), 1-acylglycerol-3-phosphate O-acyltransferase (AGPAT2) (Supplementary Table S4). The gene discussed is AACS; the disease is diabetes mellitus.