Most interestingly, we confirmed all seven proteins previously identified in two signatures by Neely et al. and Song et al. as highly expressed in late-stage tumor tissue [29] and associated with the metastasis of mccRCC tumors [30]: perilipin-2, l-lactate dehydrogenase A chain, nicotinamide N-methyltransferase, annexin A4, cofilin-1, profilin-1, and fructose-bisphosphate aldolase A (Table S2). Here, NNMT is linked to neoplasm.