A decreased proliferation rate was also observed in other cell lines with silenced transgelin expression: in SW620 [45], HT-29 and RKO [38] colorectal, MDA MB 231 breast [46], BxPC3 and SW1990 pancreatic [42], and A549 and H358 lung [43] cancer cell lines after silencing transgelin expression by RNAi. This evidence concerns the gene TAGLN and cancer.