The median serum CRP levels differed significantly between these groups (17.6 mg/L (IQR 9.5–36.9), 49.2 mg/L (IQR 10.9–231.9), respectively; p = 0.044), with lower values in PJI cases caused by low-virulence pathogens. The gene discussed is CRP; the disease is juvenile polyposis syndrome.