CRP and chronic recurrent multifocal osteomyelitis: Patients who satisfy four criteria (typical clinical symptoms, typical imaging findings, multifocal lesions or unifocal lesion within the clavicle and CRP < 30 g/L) are likely to present with CRMO, whereas in those satisfying the first two criteria but presenting with unifocal extraclavicular lesions and elevated CRP, the diagnosis should be confirmed by bone biopsy (plasma cell infiltration, fibrosis, sclerotization and negative result of microbiological testing).