In our research, there were positive correlations between PIIINP and CRP (r = 0.327; p = 0.004) and WBCs (r = 0.260; p = 0.024); their ability was studied with the ROC curve for the prediction of sepsis and showed an AUC for PIIINP equal to 0.883 with a combined sensitivity and specificity of 88% and 82% with a cut-off point of 103.3 ng/mL. Here, CRP is linked to Sepsis.