Factors that can promote the anti-tumor neutrophil phenotype include chemokines (e.g., CXCL2, CXCL5, CXCL8, CCL2, CCL3, CCL5, CXCL12 (SDF-1), CXCL16 and IL-8) alone or together with G-CSF/GM-CSF [60,61,62,200,201], TNFα [200], IFNβ [53], IFNγ [202], IFNγ together with TNFα [203], Resolvin D1 [84], hepatocyte growth factor (HGF) [168] and IL-17 [118] (Table 3). The gene discussed is CXCL2; the disease is neoplasm.