Factors that promote the pro-tumor neutrophil phenotype include TGFβ [75], VEGF [209,210], IL-11 with FOS-induced growth factor (FIGF/VEGFD) [58], IL-17 [71], IL-35 [211], IL-6 together with G-CSF [211,212], the chemokines CXCL12, CXCL14, CXCL5 and CXCL1 [58], oxysterol [213], hyaluronan fragments [214], GM-CSF [215] and macrophage migration inhibitory factor (MIF) [216] (Table 3). The gene discussed is CXCL12; the disease is neoplasm.