An interesting question that remains to be explored is to determine if, as found at the surface of splenocytes and lymph node cells of lupus mice [32], HSPA8 is also overexpressed in specific cells, especially neutrophils, in the inflamed lungs and spleen of HDM-treated mice, and whether P140 also rescues mice from this higher expression. The gene discussed is HSPA8; the disease is systemic lupus erythematosus.