As recently, the number of NK cells in the TME of NPC tumors has been shown to be of prognostic significance [41] and IFNβ, which is used as maintenance therapy in the treatment of children and adolescents with NPC, increases the ability of patients’ NK cells to kill NPC cells in vitro [16], we decided to investigate the killing of NPC cells by NK cells in the context of radiotherapy. Here, IFNB1 is linked to nasopharyngeal carcinoma.