Immunohistochemical ana-lysis indicated a strong expression of ASC, Caspase-1, Caspase-5, NLRP3, and AIM2, predominantly in sporadic infiltrating lymphoid cells and in lymphoid aggregates located in the outer media and adventitia of AAA samples (Figure 3 and [29,30]). This evidence concerns the gene CASP5 and triple-A syndrome.