RHEB and glioblastoma: Analysis of functional protein association networks of mTOR, STAT3, and CDK6 identified (PPI enrichment p-value: 4.17 × 10−8) CCNA2, CCNE1, CCND3, CCND1, Rictor, Raptor, MLST8, RHEB, and FKBP1A to be functional partners associated with their expressions and oncogenic properties in GBM (Figure 2F).