IFNA1 and HIV-1 infection: A putative direct relationship between miRNAs with a HIV-1-restriction activity and IFN were recently suggested, where inhibition of type I and type III IFN by HIV-1 infection seems to be responsible for modulating the expression of these miRNAs, and on the contrary, treatments of type I IFN in primary human monocytes and macrophages induced the expression of the HIV-1-restriction miRNAs, stands out the miR-28, miR-125b, miR-150, and miR-382 [141].