Naldini et al. [66] observed that non-hypoxic induction of HIF-1α by IL-1β in MDA-MB-231 was found to be associated with increased tumor cell migration, coupled with induction of p38 MAPK phosphorylation and CXCL8/CXCR1 expression [66]. The gene discussed is HIF1A; the disease is neoplasm.