Reports comprise the establishment of IPSCs from primary myeloblasts and T cells of patients with acute myeloid leukemia (AML) [93], from BM mononuclear cells of patients with chronic myelogenous leukemia (CML) [94], from BM cells of a T-cell acute lymphoblastic leukemia mouse model [95], from BM mononuclear cells of PTPN11 and CBL JMML patients [18,20], from skin fibroblasts of JMML patients with NS [19,22], and from blood T cells of a healthy individual and a patient with PTPN11-mutated JMML [21]. Here, PTPN11 is linked to acute myeloid leukemia.