Furthermore, Omata and colleagues [38] discovered immobility times in both the forced swim test (FST) and tail suspension test (TST), which are tests of depression-like behavior, to be reduced following GSK-3β inactivation via intra-hippocampal injections of lentivirus-expressing short-hairpin RNA targeting GSK-3β. This evidence concerns the gene GSK3B and depressive symptom measurement.