Implementation of single cell RNA sequencing (scRNA-seq) to glioma studies showed the considerable intratumoral genetic heterogeneity and mosaic expression of genes coding for surface receptors and ligands, including EGFR, PDGFRA, PDGFA, FGFR1 (fibroblast growth factor receptor 1), FGF1 (fibroblast growth factor 1), NOTCH2 (notch receptor 2), and JAG1 (jagged canonical notch ligand 1) [11]. The gene discussed is FGF1; the disease is glioma.