Interferon (IFNα) induces the expression of Slfn1, Slfn2, Slfn3, Slfn4, Slfn5, and Slfn8 in B16-F1 malignant murine melanoma cells and murine renal cell carcinoma cells (RCC) [35]. This evidence concerns the gene IFNA1 and renal cell carcinoma.