Granja and co-workers (2019) have demonstrated that Targ-CD39, consisting of CD39 fused with a single-chain antibody directed towards activated platelet integrin glycoprotein IIb/IIIa, inhibits sepsis-associated inflammatory events in mice, through the inhibition of platelets, leukocytes, and endothelial cells interaction [96]. Here, ENTPD1 is linked to Sepsis.