MTM1 and anemia (phenotype): The vertebrate functional ortholog of Mtm1 (Slc25a39) is required for iron’s integration into protoporphyrin IX to produce heme b in murine erythroid cells; its deletion induces anemia in zebrafish, cementing its role in mitochondrial iron homeostasis, while suggesting that further studies are needed to completely elucidate the role of Mtm1-related proteins [308].