NALP1 has also been explored, whereby Chen et al. (2015) examined NALP1 expressions in human normal and malignant colon tissues using a microarray assay, Western blotting and RT-PCR and explored the NALP1 expression in different cell lines and animal models of colon cancer before and after treatment with DAC (5-aza-2-deoxycytidine), an antitumor drug. Here, NLRP1 is linked to colonic neoplasm.