Liu et al. (2015) analyzed the gene expression of NLRC3, NLRC4, NLRC5, AIM2, NLRP1, NLRP3, NLRP6, NLRP12, NOD1 and NOD2 by combining a bioinformatic analysis (ten public colorectal cancer datasets from the Oncomine® Platform) and experimental, verifying utilizing clinical tissue samples during a cohort study. Here, AIM2 is linked to colorectal cancer.