In the univariate analysis of PFS and OS (Table 5), the rest of the variables analyzed (sex, age (<70 vs. ≥70 years), histology (adenocarcinoma vs. non-adenocarcinoma), brain metastasis (yes vs. no) and PD-L1 TPS (≥90% vs. <90%)) did not show statistically significant differences according to ECOG PS. Here, CD274 is linked to adenocarcinoma.