MIF has also been investigated as mediating the regulation of CD74-dependent MAPK signaling and activating cytosolic phospholipase A2 (cPLA2) [12,13], modulating tumor growth by interacting with c-Jun activation domain-binding protein-1 (JAB1) [14,15], and suppressing apoptosis associated with p53 activation and redox stress [16,17]. This evidence concerns the gene PLA2G4A and neoplasm.