The main findings regarding acute studies were: (i) IT compromises IgA secretory rate but not IgA absolute concentrations; (ii) IT promotes transitory leukocytosis (lasting up to 6 h); (iii) IT promotes lymphocytosis followed by transitory lymphopenia (lasting up to 6 h); (iv) IT promotes a transitory impairment on lymphocyte and neutrophil function. The gene discussed is CD79A; the disease is Increased total leukocyte count.