From the GenOMICC (Genetics Of Mortality In Critical Care) genome-wide association study (GWAS) [53] performed in 2244 COVID-19 critically ill patients from 208 UK intensive care units (ICUs), a significant correlation between disease severity and the presence of variants in or near genes related to antiviral response (OAS1, OAS2, OAS3 and IFNAR2) and inflammatory response (TYK2 and DPP9) was observed [53]. This evidence concerns the gene TYK2 and COVID-19.