A study of diabetic patients (56% men) with no obstructive CAD was also consistent with the current results, demonstrating that endothelium-dependent vasoreactivity, measured by coronary artery diameter response to cold pressor, correlated with urinary albumin excretion rate (r = −0.39, p = 0.0003) [26]. The gene discussed is ALB; the disease is coronary artery disorder.