For T-cell lymphoma, high novelty targets are EDEM1, CHD3, PPP1R16B, CYFIP2, CCR7, CTPS1, HNRNPUL1, FMNL1, H3F3B, ARHGEF6, DOCK11, DIAPH1, DOCK2, CTSW, BIN2, FAM120A, and DGKZ. The gene discussed is ARHGEF6; the disease is T-cell non-Hodgkin lymphoma.