CNTNAP2 and Cortical dysplasia - focal epilepsy syndrome: Disruption of CNTNAP2 is associated with autosomal recessive Pitt-Hopkins-like syndrome (also known as cortical dysplasia focal epilepsy syndrome; MIM 610042) characterized by neurodevelopmental delay, hypotonia, hyporeflexia, seizures of multiple types, neuronal migration abnormalities, autistic features, and attention deficits [27,28].