TRPM7 and Parkinson disease: Our evidence for a role of TRPM7 in synaptic vesicle endocytosis suggests that the consequence on synaptic vesicle endocytosis attributed to TRPM7 dysfunctions could be a potential molecular mechanism for TRPM7-related neurodegenerative diseases, such as Guamanian amyotrophic lateral sclerosis and Parkinson’s disease (Hermosura et al., 2005).