GPR17 and periventricular leukomalacia: As shown in Figure 4a, compared to the sham group, the wound healing rate was significantly lower in the PVL group, which was further decreased in the GPR17-overexpressed group and significantly elevated in the siR-GPR17 group (**p < 0.01 vs. sham, ##p < 0.01 vs. PVL).