WWTR1 and medulloblastoma: High expression of the transcriptional coactivator WWTR1 has been shown to be associated with a worse prognosis and affects cell proliferation in patients with medulloblastoma, regardless of subtype (Wang et al, 2019); however, phosphorylation of the S89 site leads to an inhibition of carcinogenesis and cell growth (Cordenonsi et al, 2011; Zhang et al, 2015).