MRC1 and glioblastoma: As shown in Fig. 4A and B, the tlr4f/f mice presented with an F4/80+iNOS+ M1-predominant macrophage subpopulation, whereas the tlr4f/f–lysM−cre mice exhibited an F4/80+CD206+ M2-predominant subpopulation at days 7 and 14 after anti-GBM GN induction.