Meanwhile, in the early atherosclerosis development process, TNF-α, IL-1β, IL-6, and IL-10 are closely related to the activation of JAK/STAT signaling pathway which is a signal transduction pathway that can be stimulated by cytokine and participates in the signal transduction and regulation process of various inflammatory and anti-inflammatory factors [7]. The gene discussed is IL6; the disease is atherosclerosis.