In the group of patients with steatosis, the target genes of decreased miR-16-5p and miR-195-5p are involved in Electron Transport Chain (OXPHOS system in mitochondria): Complex I—NDUFA5, NDUFB5, Complex II—SDHC, Complex III—UQCRB, UQCRFS1, lipid metabolism (genes: PRKAA2, PRKAG3, RXRA, SREBF1, GSK3B) and chemokine signaling (CXCL8) (Figure 7A and Supplementary Table 3). The gene discussed is GSK3B; the disease is steatosis.