CD274 and cancer: The cancer types with a driver alteration in the ICB target gene PD-L1 (amplification in all cases) occurring at a frequency of ≥2% were as follows (ranked from the highest to the lowest frequency): lymphoid neoplasm diffuse large B-cell lymphoma (DLBC), HNSC, SARC, BLCA, CESC, ESCA, LUSC, OV, STAD, and UCS.