For example, exosomes have been evidenced to carry toxic forms of α-synuclein (α-syn) in PD, tau and Aβ in AD, and SOD1 in ALS (Aguzzi and Rajendran, 2009; Vingtdeux et al., 2012; Schneider and Simons, 2013; Joshi et al., 2015). The gene discussed is SOD1; the disease is amyotrophic lateral sclerosis.