The results showed that the expression levels of NADH dehydrogenase, ATP synthetase 6, cytochrome oxidase B, and cytochrome oxidase I and III genes are upregulated in papillary thyroid carcinoma, whereas the expression of nuclear encoded mtTFA is not significantly changed (Haugen et al., 2003). The gene discussed is ENSG00000254051; the disease is thyroid gland papillary carcinoma.