Since a few studies have already illustrated that infected fetuses or newborns possess IgM antibodies for combating viral infection (Pulinx et al., 2020; Wu Y.T. et al., 2020), it is important to understand the conditions in pregnant women which enable SARS-CoV-2 to vertically transmit from an infected mother to her child. The gene discussed is CD40LG; the disease is viral infectious disease.