As SLC1A5-mediated glutamine transport plays a key role in tumor cell metabolism, proliferation, and ferroptosis, blocking SLC1A5 has been shown to successfully prevent tumor cell proliferation in melanoma (45), non-small-cell lung cancer (46, 47), prostate cancer (48) and acute myeloid leukemia (49). This evidence concerns the gene SLC1A5 and acute myeloid leukemia.