HPN-AS1 could be utilized in the diagnosis of prostate cancer (43); LINC00607 facilitates the proliferation and invasion of osteosarcoma (44); USP2-AS1 promotes the progression of colon cancer and ovarian cancer (45, 46); and LINC00638 and LINC00652 have been reported in nontumor diseases (47–50), while no study has revealed the function of the remaining lncRNAs. Here, HPN is linked to malignant colon neoplasm.