Common TRAEs included pleural effusion (n=10), diarrhea (n=8), rash (n=7), thrombocytopenia (n=7), neutropenia (n=7), AST elevation (n=7), ALT elevation (n=7), nausea (n=4), QTc prolongation (n=4), anorexia (n=4), paronychia (n=4), fatigue (n=4), and anemia (n=4) (Table 2). The gene discussed is GPT; the disease is anemia (phenotype).