In the validation cohort (Supplementary Figures 6C, D), the AUC of AGR (3-year AUC, 0.657; 5-year AUC, 0.671) was also higher than that of ALB (3-year AUC, 0.638; 5-year AUC, 0.618), GLB (3-year AUC, 0.606; 5-year AUC, 0.602), and TB (3-year AUC, 0.485; 5-year AUC, 0.532). The gene discussed is ALB; the disease is tuberculosis.