MMP9 and osteosarcoma: Furthermore, lnc-KASRT overexpression increased KLF6-SV1, MMP1, and MMP9 expression and decreased SRSF1 and KLF6-WT expression in osteosarcoma mice (Figures 10A–F), but lnc-KASRT downregulation showed the opposite trend (Figures 10A–F).