IFIH1 and adult acute monocytic leukemia: A recent study looking at the expression of toll-like receptor genes (TLR 2, 3, 4, 7, 8, 9) and two cytosolic gene receptors of viral nucleic acids (RIG-I and MDA5) on the acute monocytic leukaemia cell line (THP-1), found that presence of AZB activated TLR 4 and resulted in multiple activations of the MDA5 gene transcription (58).