Figure 1B and Supplementary Table 2 show the enriched terms of the upregulated genes. We found that these genes were most related to EMT, collagen formation, and the VEGFA-VEGFR2 signaling pathway. EMT plays a central role in tumor progression, and the VEGFA-VEGFR2 pathway indicates tumor angiogenesis (6, 7). Collagen formation is the basic feature of solid tumors (8). The activation of EMT and angiogenesis were also found in other sarcomas (Supplementary Figure 1 and Supplementary Table 3). This evidence concerns the gene KDR and neoplasm.