In cancer studies, by TargetScan and Gene Ontology analysis, Tao and his colleagues found that the target genes of differentially expressed miRNAs between aristolochic acid-induced upper urinary tract cancer and noncancer tissues were AKT3, FGFR3, PSEN1, VEGFa, and AR, which regulated cell proliferation and tumor progression in FGFR3 and AKT pathways (27). The gene discussed is AKT1; the disease is cancer.