GNA11 and esophageal squamous cell carcinoma: As shown in Figure 6, the mRNA level of GNA11 was higher (fold change > 1.4, p < 0.05) in ESCC patients compared with normal controls based on TCGA and GTEx data in GEPIA, which was consistent with the difference in serum level of anti-GNA11 autoantibody between ESCC patients and normal controls.