At the same time, it has been reported that ITGA2 is associated with unfavorable survival of PDAC patients by affecting the malignant biological behavior of pancreatic cancer cells (Rozengurt, Sinnett-Smith & Eibl, 2018; Shimomura et al., 2020; Yan et al., 2020). This evidence concerns the gene ITGA2 and pancreatic neoplasm.